Abstract

Review Article

Altitude sickness and Antarctic polar plateau: A review

KP Mishra* and Shashi Bala Singh

Published: 27 June, 2019 | Volume 3 - Issue 1 | Pages: 016-018

Antarctica is known for its extreme environmental conditions. It is the best model to study multiple stress factors at a time on human physiological responses. Although the coastal Antarctica is on Sea level but the Antarctic plateau or pole at high altitude. Since Antarctica is also becoming tourist site it is pertinent to have a proper understanding of altitude induced illnesses. In this review we have described the human acclimatization process at high altitude of Antarctic polar plateu and South Pole. The review also highlighted the symptoms, clinical features and prevention of altitude induced diseases. 

Read Full Article HTML DOI: 10.29328/journal.icci.1001009 Cite this Article Read Full Article PDF

Keywords:

Antarctic; South Pole; Altitude Sickness; HAPE; HACE; AMS

References

  1. Halsey LG, Stroud MA. 100 years since Scott reached the pole: a century of learning about the physiological demands of Antarctica. Physiol Rev. 2012; 92: 521-536. Ref.: http://bit.ly/2KG2SBP
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  3. Khanna K, Mishra KP, Chanda S, Eslavath MR, Ganju L, et al. Effects of Acute Exposure to Hypobaric Hypoxia on Mucosal Barrier Injury and the Gastrointestinal Immune Axis in Rats. High Alt Med Biol. 2019; 20: 35-44. Ref.: http://bit.ly/31VZubG
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  5. Mishra KP, Sharma N, Soree P, Gupta RK, Ganju L, et al. Hypoxia-Induced Inflammatory Chemokines in Subjects with a History of High-Altitude Pulmonary Edema. Indian J Clin Biochem. 2016; 31: 81-86. Ref.: http://bit.ly/2Je4tLZ
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  7. Mishra KP, Yadav AP, Sharma YK, Ganju L, Singh SB. Effect of extreme conditions of Antarctica on human leukocyte antigen-G in Indian expeditioners. Indian J Med Res. 2014; 140: 520-523. Ref.: http://bit.ly/2XBY4nk
  8. Yadav AP, Chaturvedi S, Mishra KP, Pal S, Ganju L, et al. Evidence for altered metabolic pathways during environmental stress: (1)H-NMR spectroscopy based metabolomics and clinical studies on subjects of sea-voyage and Antarctic-stay. Physiol Behav. 2014; 135: 81-90. Ref.: http://bit.ly/2FymW4T
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